e-ISSN: 2147-2181
CausaPedia - Hakemli Olgu Dergisi
e-ISSN: 2147-2181
CausaPedia - Hakemli Olgu Dergisi

Neuroleptic Malignant Syndrome and Sepsis: Differential Diagnosis in the Emergency Department

Submitted : 18.09.2020 Accepted : 30.11.2020 Published: 17.02.2021

Abstract

How often do we think of neuroleptic malignant syndrome (NMS) in patients who come to the emergency department with sepsis clinic? Due to its similarity to some organic and psychiatric disorders, this syndrome may be overlooked or difficult to diagnose. Early diagnosis and treatment gain importance in NMS and mortality can be decreased even in severe cases. In this article, we present a case of NMS that developed in a patient diagnosed with bipolar affective disorder, who had been receiving 37.5 mg / 15 days of risperidone, 300 mg / day lithium carbonate maintenance treatment for 8 years, and 2.5 mg / day olanzapine was added to his treatment 1 month ago.
Keywords: Neuroleptic Malign Syndrome , Antipsychotic Medication , Sepsis , Intensive Care

Özet

Acil servise, sepsis kliniğiyle gelen hastalarda, nöroleptik malign sendromu (NMS) ne kadar sıklıkla düşünüyoruz? Bazı organik ve psikiyatrik bozukluklara olan benzerliğinden dolayı bu sendrom gözden kaçabilir veya tanı koymak zor olabilir. NMS’da erken tanı ve tedavi önem kazanmakta olup, ciddi olgularda bile mortalite azaltılabilir. Bu yazımızda, sekiz yıldır düzenli olarak 37,5 mg/15 gün risperidon, 300 mg/gün lityum karbonat idame tedavisi alan ve 1 ay önce tedavisine 2,5 mg/gün olanzapin eklenen bipolar affektif bozukluk tanılı hasta, gelişen NMS klinik tablosu ile sunulmuştur.
Anahtar kelimeler: Nöroleptik Malign Sendrom , Antipsikotik Tedavi , Sepsis , Yoğun Bakım

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